1,4-Benzodiazepines, synthesis

Pyrrolo[2,1 -c][l, 4]benzodiazepines synthesis, 7, 614 Pyrrolo[l, 6]benzodiazocines synthesis, 7, 515 Pyrrolo[3,4-c]benzopyrazoles reactions, 6, 1034 Pyrrolobenzothiazoles synthesis, 4, 785 Pyrrolo[l, 2-c]benzotriazines synthesis, 4, 240 Pyrrolo[3,4-c]cinnolines synthesis, 4, 240... 

Benzodiazepine synthesis has been reviewed (B-91MI906-01). The method generally applied the appropriately o-disubstituted benzene with a 1,3-bis carbon electrophile, e.g. o-phenylenedia-mine + RCOCHR COR — (389) — (390) for 1,5-benzodiazepines. 

---