Chromatographic simulation

Juza, M., Development of an high-performance liquid chromatographic simulated moving bed separation from an industrial perspective, /. Chromatogr. A, 865, 35, 1999. 

Sulfur compounds in the gas oil fractions from two bitumens (Athabasca oil sand and Cold Lake deposit)> a heavy oil (Lloydminster) from Cretaceous reservoirs along the western Canada sedimentary basin, and a Cretaceous oil from a deep reservoir that may be mature (Medicine River) are investigated. The gas oil distillates were separated to concentrates of different hydrocarbon types on a liquid adsorption chromatographic column. The aromatic hydrocarbon types with their associated sulfur compounds were resolved by gas chromatographic simulated distillation and then by gas solid chromatography. Some sulfur compounds were further characterized by mass spectrometry. The predominant sulfur compounds in these fractions are alkyl-substituted benzo- and dibenzothiophenes with short side chains which have few dominant isomers. 

Chromatographic Separations. The distillates from the oils were separated first by liquid chromatography, then by gas chromatographic-simulated distillation according to boiling point, and finally by gas chromatography on lithium chloride-coated silica, as shown in Figure 2. 

GAS CHROMATOGRAPHIC SIMULATED DISTILLATION (FIDl AND MICROCOULOMETRIC DETECTORS)... 

Biressi, G., Quattrini, F., Juza, M., Mazzotti, M., Schurig, V., and Morbidelli, M. (2000) Gas chromatographic simulated moving bed separation of the enantiomers of the inhalation anesthetic enflurane. Chem. Engineer. Sci. 55, 4537-4547. 

Organic acid removal by resin separation in a chromatographic simulated moving... 

Meinert, T. and Lunze, J. (2008) Decentralised control of chromatographic simulated moving bed processes based on wave front reconstruction. /. Process Contr., 18, 780-796. 

Juza, M. Di Giovanni, O. Biressi, G. Schurig, V. Mazzotti, M. Morbidelli, M. Continuous enantiomer separation of the volatile inhalation anesthic enflurane with a gas chromatographic simulated moving bed unit. J. Chromatogr. A, 1998, 813, 333-347. 

Gas chromatograph simulated distillation (9) was used to determine the boiling range of the products. 

In many cases distribution functions are determined experimentally the characterization of petroleum fractions by true-boiling-point distillation or gas-chromatographically simulated distillation, and the characterization of polymers by gel-permeation chromatography. In principle, the integrals of continuous thermodynamics may be directly solved based on these experimentally determined distribution functions. However, this approach delicate numerical analyses and the assumption the complete distribution function has been obtained by experiment clearly this is no the case, for example, for some polymers only molar-mass averages are determined. Thus, there are numerous cases where smoothed or analytical distribution function provides more reliable phase equilibrium calculation than those obtained by use of the experimentally determined distribution function. When the integrals of continuous thermodynamics possess analytical solutions considerably numerical simplification is afforded and this is one motive for the desire to have analytical expressions for the distribution function. 

Figure 4.14 shows a screen dump of an isothermal gas chromatographic simulation from a commercial gas chromatographic optimization program. The Temperature, Pressure, and Column tabs in the display permit the user to set elution conditions, including multiramp temperature and pressure programming, which were not exercised for this example. The Auto-Optimize tab carries out a minimum-resolution-oriented optimization calculation, which determines a set of conditions that lie within specified limits and meet the minimum resolution criterion. 

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