Christmas rose

The bufadienolides occur in plants as well as animals, but only in plants are they in the form of glycosides. Their 3-hydroxyl group is attached lo glucose, rhamnose, or thevetosc. Hellebrigenin (Fig. 2). which is also known as bufotalidin. occurs in the rhizomes of the Christmas rose and other Helleborus species in the form of a rhamnoside. Bufadienolides have so far been found in plants in only two families, the buttercup and the lily family. 

Helleborus niger Black hellebore, Christmas rose Helleborcin Also called melampodium after the Greek physician Melampus, who used it as a purgative... 

Hellebores flower in winter and early spring, earning names such as Christmas rose i Helleborus niger) or Lenten rose (H. orientalis). Most have green, creamy white, or dull purple blooms, carried over low evergreen foliage. 

CHRISTMAS ROSE Helleborus ni er, L., Family Ranunculaceae, is cultivated in gardens. The whole plant is toxic. Especially in the root there are cardiac glycosides, which are very stable. They are not degraded by drying or storage. The symptoms are the same as for Foxglove. 

Large-scale production commenced on Christmas Day 1940 and rose eventually to an output of about 500 L of culture fluid per week, from which around 100-200,000 units of penicillin activity could be obtained. By the end of January 1941, enough penicillin had been accumulated to initiate a small-scale clinical trial. It is worth noting that these gargantuan efforts had been carried out while Britain struggled to survive following the evacuation from Dunkirk (in May 1940), the Battle of Britain (September) and the everpresent fear of invasion. 

Industry and Business Sectors. Computer science has led to the creation of electronic retailing (e-tailing). Online sales rose 15.5 percent in 2009, while brick and mortar (traditional) sales were up 3.6 percent from the previous year. Online-only outlets such as Amazon.com have been carving out a significant part of the retail market. Traditional businesses, such as Macy s and Home Depot, are finding that they must have an online presence. Online sales for the 2009 Christmas season were estimated at 27 billion. 

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