Chondrodendron tomentosum plant Tubocurarine chloride

Chondrodendron tomentosum plant, by extraction Tubocurarine chloride Cytidine-5 -monophosphate, by fermentation Citicoline... 

These results seemed to establish with certainty that the active component of tube curare is derived from Chondrodendron tomentosum, but the matter again became doubtful when King reported that in the stems of a carefully authenticated specimen of the plant, collected at Tarapoto in Peru, he had found 1-curine and Z-tubocurarine chloride. This is the first recorded natural occurrence of the latter and seems to indicate either that the alkaloidal components of the plant are not constant in character, or that the botanical description of Chondrodendron tomentosum covers two species containing the dextro- and Icevo- quaternary alkaloids respectively. 

In 1939 King (123) obtained both the leaves and liana of the plant amphi huasa (poison rope) which is used by the Indians near Tarapoto in northern Peru for the preparation of curare. It was identified as Chondrodendron tomentosum, and chemical examination showed that it contained Z-curine (Z-bebeerine) and Z-tubocurarine chloride and not d-tubo-curarine chloride as expected. However Wintersteiner and Dutcher (81)... 

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