Chloro hexafluorophosphate

The vaulted iron(II) cyclidene complexes were easily isolated as orange to red crystalline bis(hexafluorophosphate) salts or chloro hexafluorophosphate salts. The extreme air sensitivity and proclivity toward capturing varying numbers of molecules of solvent led to difficulties in obtaining simply definable and reliable elemental analyses. However, careful work led to pure samples and elemental analysis was an important part of the characterization of these compounds (see Experimental Section). Magnetic moments were determined by the Evans method at 25°C in acetonitrile solution [Fe VMe(3,6-durene) Cl]PF6, 5.0BM [Fe VC5H (3,6-durene) ](PF6)2, 4.87BM [Fe VPh(9,10-... 

Lipases from C. antarctica and P. cepacia showed higher enantioselectivity in the two ionic liquids l-ethyl-3-methylimidazolium tetrafluoroborate and l-butyl-3-methylimidazolium hexafluoroborate than in THE and toluene, in the kinetic resolution of several secondary alcohols [49]. Similarly, with lipases from Pseudomonas species and Alcaligenes species, increased enantioselectivity was observed in the resolution of 1 -phenylethanol in several ionic liquids as compared to methyl tert-butyl ether [50]. Another study has demonstrated that lipase from Candida rugosa is at least 100% more selective in l-butyl-3-methylimidazolium hexafluoroborate and l-octyl-3-nonylimidazolium hexafluorophosphate than in n-hexane, in the resolution of racemic 2-chloro-propanoic acid [51]. 

Workers at Merck recently reported three variants for pyridine formation in conjunction with the synthesis of COX-2-Specific inhibitor 8 (Scheme 1). Acid catalyzed annulation (path a) was achieved in 72% with 2 equivalents of methanesulfonic acid and four equivalents of 2-chloro-3-aminoacrolein. Base-promoted annulation between 7 and 2,3-dichloroacrolein provided 8 in 58% yield. Finally, base-promoted annulation with 2-chloro-iV,jV-dimethyl-armnotrimethinium hexafluorophosphate afforded 8 in 97% yield . Other alkylation-based strategies for pyridine formation include the work of Manna <00BMC1883> and Parra <00S273>. 

Recently, the use of pentamethylcyclopentadienyl(l,10-phenanthrohne-5,6-di-one)chloro rhodium(III) hexafluorophosphate [(Cp )Rhm(phend)Cl]PF6, 11 (Fig. 43.4) has been reported for the electrochemical NAD+ reduction. TONs between 7 and 453 h-1 have been achieved by varying pH, temperature and the complex concentrations [44]. This study reveals only preliminary results, so the mechanism of cofactor reduction is not explained however, due to the structural... 

Fig. 43.4 Pentamethylcyclopentadienyl(1,10-phenanthroline-5,6-dione)chloro rhodium (111) hexafluorophosphate (11).

F. TRIS(ACETONITRILE)CHLORO(n4-l, 5-CYCLOOCTADIENE)-RUTHENIUM(II) HEXAFLUOROPHOSPHATE(l—)... 

Kiso s synthetic strategy follows the work of Heathcock [8]. He also uses titanium tetrachloride as the reagent for the multiple ring closure. His work focusses on an effective preparation of the peptide precursor for the multiple ring closure. For this purpo.se he introduces a new coupling reagent 2-chloro-l,3-dimethylimidazo-lidium hexafluorophosphate (CIP) 81 (Scheme 20). 

Recently, Fiirsmer extended the method of Stone to chloroimidazoltnium salts. Oxidative addition of 2-chloro-1,3-dimethyltmidazolinium hexafluorophosphate (145) onto Pd(PPh3)4 gave the cationic [(NHC)PdCl(PPh3)2]PF6 (146) in 72% yield (equation 21). 

Vinamidinium salts are important intermediates in the synthesis of heterocycles. The 2-chloro-l,3-bis(dimethylamino)trimethinium hexafluorophosphate salt has been used in the preparation of the highly selective Cox-2 inhibitor etoricoxib (Scheme 1). This method describes a straight-forward preparation of the hexafluorophosphate salt which is a crystalline, thermally and shock-stable, non-hygroscopic solid. The submitters have extensively studied the preparation of vinamidinium salts and demonstrated that the method is applicable to substituted acetic acids that contain an electron-withdrawing group (Table 1)." The annulation reaction is also general and useful for the preparation of pyridines, pyridones and pyridine N-oxides. ... 

Methanaminium, N-[2-chloro-3-(dimethylamino)-2-propenylidene]-N-methyl-, hexafluorophosphate(l-... 

KETONES Lithium diisopropylamide. Nickel carbonyl. Sodium tetiacarbonyl-ferrale(-II). Thallium(IIl) nilrale. 2,4,4,6-Tetramethyl-5,6-dihydro-l,3-(4/0-oxazine. Triphenylmcthyl hexafluorophosphate. y-KETONlTRILES Sodium cyanide. d-LACTONES Silver nitrate. 7-LACTONES a-Chloro-N-cyclohexylpro-panaldoximc. 

CIFgN4PZnC24H2g, Zinc(II), chloro(2,9-di-methyl-3,10-diphenyl-l, 4,8,11-tetraaza-cyclotetradeca-1,3,8,10-tetraene)-, hexafluorophosphate(l -), 22 111 CIFgTlCi2H2, Thallium(III), chlorobis-(2,3,4,6-tetrafluorophenyI-), 21 73 CIF9OC4, Hypochlorous acid, perfluoro-tert-butyl ester, 24 61... 

Nb2Cl8S3Ci6H,8, Niobium(III), di-p-chloro-tetrachloro-)jL-(dimethylsulfide)-bis(dimethyl sulfide)di-, 21 16 NdCb, Neodymium chloride, 22 39 NdF,8N606Pi2C72H72, Neodymium(III), hex-akis(diphenylphosphinic amide)-, tris(hexafluorophosphate), 23 180 NdN30i3C8Hi6, Neodymium(III), trini-trato( 1,4,7,10-tetraoxacyclododecane)-, 23 151... 

However, S. I. Schlesinger found that epoxides could be polymerized by a wide variety of diazonium salts, including p-chloro-benzenediazonium hexafluorophosphate, on exposure to ultraviolet radiation (16, 17). He delineated differences in behavior between various salts and identified those which are most effective in promoting rapid polymerization to high molecular weight. In particular, he showed that the hexafluorophosphates are much more effective as photoinitiators than the tetrafluoroborates (18). 

IiClP3Ci7H4i, Iridium, chloro(n2-cyclooc-tene)tris(trimethylphosphine)-, 21 102 I1CIP4C12H32, Iridium(l + ), bis[l,2-ethanediyl-his(dimethylphosphine) -, chloride, 21 100 IrFI2N40P4C40H3 , Iridium(III), tris(acetoni-trile)nitrosylbis(triphenylphosphine)-, bis[hexafluorophosphate], 21 104... 

HCTU l-[bis(dimethylamino)methylene]-6-chloro-l H-benzotriazolium hexafluorophosphate 3-oxide... 

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