Chitobiose octaacetate

Crab, shrimp, and lobster shells, waste products of the sea food industry, are the best sources of the polysaccharide. Calcium carbonate is first removed by hydrochloric acid and then protein and other organic impurities by extraction with sodium or potassium hydroxide solutions. Complete acid hydrolysis of chitin, although requiring drastic conditions, yields almost theoretical amounts of D-glucosamine and acetic acid (Chapter VIII), whereas controlled acid or enzyme hydrolysis produces V-acetyl-D-glucosa-mine. Acetolysis of chitin or acetylation of the partial acid hydrolysis products gives among other products chitobiose octaacetate which has been... 

The simple analogues (36) of the natural mannosyl transferase acceptor substrate (GlcNAc)2 pyrophosphate-dolichyl have been synthesized from chitobiose octaacetate (35) as shown in Scheme 6. ... 

This conclusion. has been reached mainly from crystallographic studies on chitin and on acetylchitobiose obtained from chitin by acetoly-sis. The chitobiose was isolated in the form of its crystalline octaacetate which could also be obtained by acetylation of the hydrolyzate produced by the action of fuming hydrochloric acid on chitin. A hen-decaacetylchitotriose also was obtained by this procedure. 

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See also in sourсe #XX -- [ ]

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