Chiral Assemblies Comprising Enantiopure Building Blocks

Chiral Assemblies Comprising Enantiopure Building Blocks 

This section presents different kinds of chiral supramolecular aggregates based on various scaffolds endowed with stereogenic centers. This is the easiest approach to chiral supramolecular systems—present also in Nature— because of the high level of steric control that it permits. 

Achiral fm-Melamine with Chiral Cyanurate Assembly 

One of the earliest examples of chiral melamine-cyanurate was reported by Whitesides and collaborators, who studied the hydrogen-bonded aggregate between three molecules of chiral cyanurate and a complementary achiral fr/ s-melaminc unit based on a 1,3,5 trisubstituted benzene with a melamine unit appended at each arm (Fig. 5) [20]. The fris-mclaminc unit is not chiral itself, but in the complex with cyanurate forms a tightly bonded hydrogen bond platform with C3 symmetry which is chiral at a supramolecular level due to the clockwise (P) and counterclockwise (M) conformation of the pendants (Fig. 5). 

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Chiral Assemblies Comprising Enantiopure Building Blocks... 

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