Chinese site selection

The muscarinic receptor subtype selectivity was assessed by employing receptor binding assays [49, 51]. [3H]N-methylscopolamine was used to label native muscarinic M2> M3 and M4 receptors binding sites of rat heart, submaxillary gland, and NG 108-15 cell homogenates, respectively, and to label cloned human muscarinic mj-ms receptors expressed in Chinese hamster ovary cells. [ H]Pirenzepine was the tracer to label muscarinic Mi receptors binding sites of rat cerebral cortex. 

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