Chemspeed automated synthesizer

Fig. 4 Illustration of (a) Chemspeed automated synthesizer and (b) Symyx batch polymerization system for synthesis of discrete polymer libraries. Reprinted with permission from [90], (Copyright 2007 Taylor Francis Group, http //www.informaworld.com)...

C-E bond formation via hydroalumination, 10, 859 C-E bond formation via hydroboration, 10, 842 olefin cross-metathesis, 11, 195 terminal acetylene silylformylation, 11, 478 Chemspeed automated synthesizer, for high-throughput catalyst preparation, 1, 356 Chini complexes, characteristics, 8, 410 Chiral bisphosphanes, in hydrogenations on DIOP modification, 10, 7... 

Fig. 7 Automated synthesizers Chemspeed ASW 2000, Zinsser SOPHAS, aapptech The Solution and Model 384, as well as the fully automated lab offered by Accelab.

Chemspeed s PSWllOO offers synthesis in independent glass reactors (up to 80) of sizes from 13 mL to 100 mL. It is one of the most flexible synthesizers, allowing a variety of reaction conditions (preactivation, elevated temperature) and protocols and is capable of the automated cleavage of the final peptides, evaporation of the solution, and connecting to HPLC. Figure 4 provides more details of this synthesizer. 

A suitable automated preparation system providing almost all features was found in the "Accelerator Synthesizer" platform from Chemspeed Technologies. Equipped with 24 lOOml-glass-vessels, two heating zones, solid and liquid dosing unit, evaporator, and "filtration-to-waste" option, the system allows conducting the necessary basic preparation steps with the desired sample size. A pH control system was additionally developed by Degussa. 

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