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Chemopreventive activity methods

Inhibition of mutagenesis and inhibition of the tumor promotion/ progression have been used as screening methods for the discovery of potent chemopreventive agents. Chemotherapeutic agents in the contrary are administered in order to kill the formed tumor. In vitro cytotoxic or growth inhibitory activity on tumor cells as well as in vivo antitumor activity on transplanted tumors in animals are useful test systems for the discovery of potential antitumor agents. [Pg.210]

The compounds from the ethyl acetate fraction showing strong apoptosis-inducing activity were identified by spectral methods as epidioxysterols. The in vitro results suggest that induction of apoptosis by epidioxysterols may provide a pivotal mechanism for its cancer chemoprevention. [Pg.384]

See other pages where Chemopreventive activity methods is mentioned: [Pg.591]    [Pg.327]    [Pg.185]    [Pg.29]    [Pg.379]    [Pg.515]    [Pg.216]    [Pg.264]    [Pg.292]    [Pg.3]    [Pg.36]    [Pg.1]    [Pg.193]    [Pg.228]    [Pg.127]    [Pg.166]    [Pg.110]   
See also in sourсe #XX -- [ Pg.591 ]



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