Chemokine viral analogs

By analogy, one could speculate that ECRF3 sensitizes T cells to CXC chemokines to regulate proliferation of virally infected cells. In this regard, it is important to recall that HVS causes fatal T-cell lymphomas and leukemias when introduced into nonnatural primate hosts. Whereas other HVS ORFs, including STP, which encodes the saimiri transformation-associated protein, are known to be necessary for HVS transforming... 

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