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Proteomics chemical libraries

Mass spectrometry (MS) is playing an increasingly visible role in the molecular characterization of combinatorial libraries, natural products, drug metabolism and pharmacokinetics, toxicology and forensic investigations, and proteomics. Toward this end, electrospray ionization (ESI), atmospheric pressure chemical ionization (APCI), and atmospheric pressure photo-ionization (APPI) have proven valuable for both qualitative and quantitative screening of small molecules (e.g., pharmaceutical products) [9-14]. [Pg.606]

Mitsopoulos G, Walsh DP, Chang YT. Tagged library approach to chemical genomics and proteomics. Curr. Opin. Chem. Biol. 2004 8 26-32. [Pg.585]

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Chemical libraries

Chemical proteomics