Chemical communication system of the green flagellate, Chlamydomonas

2 Chemical communication system of the green flagellate, Chlamydomonas 

1) recryst n of the cyclohexylamine salt from MeOH, /-PrOH 

Chemical Synthesis of Hormones, Pheromones and Other Bioregulators 

Kuhn s theory was revolutionary, because they claimed that chemical substances could regulate such a basic biological process as reproduction and also that a mixture of two isomers, not a single pure compound, was responsible for the bioactivity. Their work attracted attention of scientists in many countries, and in 1951 I myself read a review article on this work, and became fascinated by the beauty of the chemical communication system of the organism. 

In 1995 Starr el al. in the USA reported the chemoattraction of male gametes by female gametes of a new species of the green flagellate, Chlamydomonas allensworthii. The female-produced attractant pheromone was isolated and identified as 168 by Jaenicke and Marner in Germany. They coined the name lurlenic acid to 168, because they worked in Cologne near the Rock of Lorelei. The pheromone 168 attracts the male gametes at a concentration as low as 10-12M. 

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