Charge phospholipid headgroups

Previous studies have shown that surfactant vesicles and tubules can be metallized in a nonselective manner. Since phospholipids with negatively charged headgroups bind metal ions much more strongly than phospholipids with zwitterionic headgroups, Che Pdbind selectively to the negatively charged phospholipids. As a result, selective metallization should occur. 

Image-charge models. These models take into account the discreteness of surface charges, which induces orientation in the adjacent water dipoles [574-577]. Dipoles due to zwit-terionic surface groups, for example, phospholipid headgroups [578], have been also taken into consideration in models of the electrostatic interaction between planar dipole lattices [579-583]. 

Seelig, I. (1993). Phospholipid headgroups as sensors of electric charge, In New Developments in Lipid-Protein Interactions and Receptor and Function (K. W. A. Wirtz, ed.). Plenum Press, New York. 

FIG. 9 Simulated electrical potential and space charge density profiles at the water-1,2-DCE interface polarized at/= 5 in the absence (a) and in the presence (b) of zwitterionic phospholipids. The supporting electrolyte concentrations are c° = 20 mM and c = 1000 mM. The molecular area of the phospholipids is 150 A, and the corresponding surface charge density is a = 10.7 xC/cm. The distance between the planes of charge associated with the headgroups is d = 3 A. 

The arrows indicate the effect of increase in the corresponding parameter on fluidity. Depends on membrane phospholipid composition (headgroups negatively charged). 

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