Cellular spin resonance

ABSTRACT A brief history of the behavior of materials in nonuniform electrical fields is presented, followed by a theory of dielectrophoretic force and the derivation of the general force equation. Attention is paid to the several classes of polarization which lead to the experimental considerations of induced cellular dielectrophoresis. A distinction between batch and continuous methods is discussed, with a focus on a new microtechnique. While dielectrophoresis can induce aggregation of materials, i.e., cells, other orientational applications exist. Cell division, cellular spin resonance, and pulse-fusion of cells form topics appropriate to the realm of high-frequency electrical oscillations and are discussed in the context of living material. 

In summary, the presence of natural rf oscillations by cells is confirmed (a) by the preference of (dividing) cells for accumulating particles of high DK over that for ones of low DK (b) by the predicted suppression of this by salt effect (c) by the predicted increase of this by poling (d) as we shall see, by cellular spin resonance " and (e) by direct detection. " ... 

Maja Mischel, Arthur Voss, and H. A. Pohl, Cellular Spin Resonance in Rotating Electric Fields, J. Biol. Phys. 10, 223-226 (1983). 

Rotation also occurs in nonrotating external fields, and onset is often at a sharply well-defined frequency. The rotation is therefore also called cellular spin resonance. One... 

Cellular spin resonance indicates various physiological states of living or dead cells, and also represents a method for cellular manipulations. It should, for example, be possible to rotate intracellular organelles with respect to the whole cell. 

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