Cellular responses, trained muscle

Cellular Responses In Trained Muscle. Recent evidence, obtained from appropriate measurements of metabolites within the cell during contractions, suggests that skeletal muscle of trained individuals Is better able to adjust, as compared to skeletal muscle of untrained Individuals, to the energy demands of a submaxlmal contraction effort. This Is apparent since metabolic conditions altered by contractions within trained muscle change less than in untrained muscle from that found at rest. For example, the PCr content of... 

Hypertrophy is an increase in the size of the cells due to synthesis of more sub-cellular components. An increase in the size of the organ results. Take, for example, cardiac hypertrophy in response to increased workload. The increased load is often a result of some pathological condition such as heart valve incompetence or stenosis of an outflow path. Hypertrophy of the muscles of a body builder is another good example, in which the increased workload is due to continued weight training. 

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