Cell plasma membrane physical organization

This system is organized in vascular plants as a 30 nm diameter plasma membrane complex, known as the rosette TC, that was first described by Mueller and Brown more than 25 years ago [42]. The rosette is composed of an estimated 36 subunits comprising at least three types of cellulose synthase A proteins. All three components have been shown to be essential for correct assembly and enzymatic activity of the complex in Arabidopsis [43, 44]. The physical interaction of these three components has recently been demonstrated by bimolecular fluorescence complementation [45]. The system also offers a beautiful example of the functional aspects of this organization, as cortical microtubules guide the movement of cellulose synthase complexes through the plasma membrane during cell wall biosynthesis [46,47],... 

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