Cell macroencapsulation

The inclusion of cells into functional biomaterial scaffolds carries several critical requirements. During and after the macroencapsulation process, cells must remain viable and physiologically functional. It is desirable to encapsulate as many cells as possible and... 

Further research examining the transplantation of pancreatic islet cells identifies this approach aimed at curing type 1 diabetes. Unfortunately, the loss of cell function following transplantation presents a major issue. Macroencapsulation of cells in order to isolate and protect them from immune responses have proven unsuccessful, resulting in hypoxic death due to poor diffusion of essential molecules. Nanoencapsulation has been shown to allow for sufficient molecular permeability without significant... 

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