Cell culture models heterogeneous cells population

The unstructured and segregated model considers the cell culture as a heterogeneous population, with individual cells characterized by age, mass, or size. The variation of properties follows a statistical distribution. The most concise way to deal with such population heterogeneity is through a population balance model (PBM). These models can become mathematically complex because the equations that describe the population have to consider that the properties vary in the population and... 

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