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CD95 signaling pathways

R., 1995, Multiple pathways originate at the Fas/APO-1 (CD95) receptor sequential involvement of phosphatidylchohne-specificphosphohpase C and acidic sphingomyehnase in the propagation ofthe apoptotic signal. EMBO J. 14 5859-5868... [Pg.241]

Extrinsic (death receptor) pathway of caspase activation during apoptosis involves the binding of death ligands to cell surface receptors (e.g., Fas/ CD95/Apo-l or TNF receptor), recruitment of adaptor molecules Fas-associated death domain (FADD) or TNF receptor-associated death domain (TRADD) to the cytosolic end of the receptor, and formation of the death-inducing signaling complex (DISC) at the plasma membrane. DISC recruits and activates the initiator caspases, caspase-8 or -10. [Pg.14]

See other pages where CD95 signaling pathways is mentioned: [Pg.301]    [Pg.525]    [Pg.553]    [Pg.301]    [Pg.525]    [Pg.553]    [Pg.4]    [Pg.16]    [Pg.232]    [Pg.298]    [Pg.64]    [Pg.314]    [Pg.2]    [Pg.14]    [Pg.232]    [Pg.298]    [Pg.180]    [Pg.217]    [Pg.161]    [Pg.83]    [Pg.6]    [Pg.524]    [Pg.526]    [Pg.235]    [Pg.126]    [Pg.53]    [Pg.176]    [Pg.271]    [Pg.285]    [Pg.70]    [Pg.120]    [Pg.42]    [Pg.32]    [Pg.206]    [Pg.318]    [Pg.207]    [Pg.231]    [Pg.238]    [Pg.239]    [Pg.291]    [Pg.298]    [Pg.300]    [Pg.194]    [Pg.344]    [Pg.231]    [Pg.238]    [Pg.239]    [Pg.291]   
See also in sourсe #XX -- [ Pg.301 ]

See also in sourсe #XX -- [ Pg.301 ]



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