Cationic graft copolymer

A Cationic Graft Copolymer of Lignin. The applications of the anionic graft copolymers described above are many but the negative charge on the polymer or the behavior of the anionic polymer under application conditions often limit the utility of these materials. 

Lignin has been reacted with 4N,4N - dimethyl-4-ammoniumhept-1,6 -diene chloride monomer to make a cationic graft copolymer. The structure of the copolymer is illustrated by the formula ... 

Table 6 Synthesis and Application Data for Cationic Graft Copolymer A Synthesis Data...

In addition to a better understanding of the effect of reaction variables on products, rates and molecular weights, this work has also led to new mechanistic concepts such as termination by hydridation and to the optimization of cationic graft-copolymer synthesis. 

Dautzenberg H, Konak C, Reschel T, Zintchenko A, Ulbrich K. Cationic graft copolymers as carriers for dehvery of antisense-oligonucleotides. Macromol Biosci 2003 3 425-435. 

Furthermore, Yuan et al. [144] introduced spherical PEC particles obtained by complexation of the cationic graft copolymer PEI-gra/t-poly(A-vinylpyrrolidone) (PEI-g-PVP) with anionic block copolymer of PVP-h/oc -poly(2-acrylamido-2-methyl-l-propanesulfonic acid) (PVP-6-PAMPS) the particle size was around 140 nm. Folic acid was entrapped in the micelle core by electrostatic attraction and the release rate was strongly dependent on the pH of the release medium. 

A similar system has furthermore been investigated by Gohy etal. [215,245] in the case of complex formation between P2VP-PEO and PEO-PMAA diblock copolymers as well as for combination of a PS-P2VP-PEO triblock with a PAA-PEO comb-block copolymer. The same concept was applied by Tenhu and co-workers [273] involving PEO-PMANa anionic block copolymer and a cationic graft copolymer. 

Prepare the wash solution (not supplied either 1 PBS or 1 HBSS) Warm wash solution and the cationic graft-copolymer 37. ... 

Add the DNA/ (the cationic graft-copolymer) mixture to cells. Swirl plate to distribute. ... 

Dulbecco s modified Eagle s medium supplemented with 10% fetal calf serum, 0.1 mM nonessential amino acids, 5 mMl-glutamine, and antibiotics (100//g/mL streptomycin, 100 U/mL penicillin) An aq. solution of cationic graft-copolymer having a thixotropy property, a strong sheer stress is needed for its solution to flow and wet the cell. It is better to use Incubator shaker. If necessary, 0.1iA-5iA of SDS supplement for toxi-blocking can be added to medium until cytotoxicity is apparent. Do not reverse its order. 

---