Caspase 3-catenin

B12. Brancolini, C., Lazarevic, D., Rodriguez, J., and Schneider, C., Dismantling cell-cell contacts during apoptosis is coupled to a caspase-dependent proteolytic cleavage of beta-catenin. J. Cell Biol. 139, 759-771 (1997). 

Some caspase substrates, such as catenins, cadherins, plakoglobin, and des-moglein, maintain cell adhesion and cell-cell communications in adherens and gap junctions, or in desmosomes. Cleavage of these proteins causes loss of contact between cells [78, 79]. 

Ling Y, Zhong Y, Perez-Soler R. Disruption of cell adhesion and caspase-mediated proteolysis of beta- and gamma-catenins and APC protein in paclitaxel-induced apoptosis. Mol Pharmacol 2001 59 593-603. 

Caspase-3 CPP32, Yama, apopain PARP, SREBs, ICAD Gelsolin, Caspase-6, Caspase-7, Caspase-9, DNA-PK, MDM2, Gas2, Fodrin, jS-Catenin, Lamins, NuMA, FAK, p2l " HnRNP proteins, Topoisomerase 1, Calpastatin, Presenelin2 Apoptosis... 

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