Heavy metals cardiovascular system

Mean arterial pressure and cardiac output, an expression of the amount of blood that the heart pumps each minute, are the key Indicators of the normal functioning of the cardiovascular system. Mean arterial pressure is strictly controlled, but by changing the cardiac output, a person can adapt, e.g., to increased oxygen requirement due to increased workload. Blood flow in vital organs may vary for many reasons, but is usually due to decreased cardiac output. However, there can be very dramatic changes in blood pressure, e.g., blood pressure plummets during an anaphylactic allergic reaction. Also cytotoxic chemicals, such as heavy metals, may decrease the blood pressure. 

Heavy metal exposures are well known to impact the cardiovascular system. Workers exposed to manganese have been found to have accelerated heart beats and mean diastolic heart blood pressures that are significantly lower than those of controls. Mercury and cadmium exposures are associated with hypertension, vascular disease, and myocardial infarction (heart attack). I23 There is a causal relationship between lead exposure and hypertension. I24l... 

As we have seen the morbidity cases of respiratory and alimentary systems highlight the inter-correlation between biogeochemical food web, pollution loading and human health. However, the physiological response of central nervous and cardiovascular systems to heavy metals and pesticides is also known and the relevant analysis of morbidity of cardiovascular system and psychological distresses was carried out in 1991-1997 in the industrial area of Crimea—Armyansk city, Ukraine (Evstafieva et al, 1999). The correlation between morbidity of a respiratory system and pollutants emissions was found (Figure 6). 

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