Cardenolide genins

Faust, T., Theurer, C., Eger, K. and Kreis, W. (1994) Synthesis of uridine 5-(a-D-fucopyranosyl diphosphate) and (digitoxigenin-3(3-yl)-p-D-fucopyranosideand enzymatic p-D-fucosylation of cardenolide genins in Digitalis lanata. Bioorg. Chem., 22, 140-9. 

D In UV-365 nm, however, a spectrum of about 20 blue fluorescent zones from Rf 0.05-0.95 is. seen, with a specific dark-blue fluorescence of lanatoside A and purpurea glycoside A. Green (vis) or red (UV-365 nm) zones at Rf 0.85 are due to chlorophyll, and yellow zones at the solvent front are due to flavonoids or anthraquinones (e.g. digilutein), which to some extent overlay the cardenolide genins. 

Am leichtesten deutbar sind noch die Spektren der freien Genine. Cardenolide, die wie das Digitoxigenin (266) Hydroxylgruppen in der Stellung 3 und 14 enthalten 6>, geben ein charakteristisches Bruchstiick der Masse 203, C15H23 (267), das das ABC-Ringsystem enthalt. 

Cardiac glycosides consist of a five-ring cardenolide aglycon, called a genin, with a number of attached monosaccharides, which often include deoxysugars. These steroidal compounds are usually isolated from plant material (digitoxin, strophantidine), but they have been dis-... 

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