Carcinogen-deoxyribonucleic acid adduct

The remarkable progress achieved by Vouros et al. [120,121] in the CEC analysis of isomeric polyaromatic hydrocarbon deoxyribonucleic acid (DNA) adducts derived from in-vitro reactions of carcinogenic hydrocarbons with calf thymus DNA has been illustrated in a previous section. This work represents an... 

If substance transportation inside a cell takes place, reactive chemicals can react with the cell components. Of special importance are adducts with DNA (deoxyribonucleic acid), which carries the full genetic information. Reactions with DNA can in principle cause carcinogenic effects. A discussion of these effects is given in Section 3.3.3. 

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