Carboprost tromethamine

Adverse reactions to the prostaglandin analogue carboprost tromethamine include all of the following EXCEPT... 

Ophthalmic drops 0.03% solution Carboprost tromethamine (Hemabate)... 

Levine LA, Jarrard DF. Treatment of cyclophosphamide-induced hemorrhagic cystitis with intravesical carboprost tromethamine. J Urol 1993 149(4) 719-23. 

PGF2 is available for clinical gynecologic use. This drug, carboprost tromethamine (15-methyl-PGF2ct the 15-methyl group prolongs the duration of action) was withdrawn from the United States market. Carboprost is used to induce second-trimester abortions and is usually administered as a single 2.5 mg intra-amniotic injection. The abortion is normally completed in less than 20 hours. 

Intramuscular injection of carboprost tromethamine can also be used to induce abortion. Unlike the one-time intrauterine instillation of dinoprost, carboprost is given repeatedly up to the total dose of 2.6 mg normally required to cause abortion. Intra-amniotic administration has close to a 100% success rate, with fewer and less severe adverse effects than intravenous administration. 

Common Name Carboprost Trometamol Carboprost Tromethamine Prostodin... 

Carboprost Tromethamine. Carboprost tromethamine, l5-l )-nicthyl-PGF2 (Hcmabate), is a prostaglandin derivative that has been mtxlified to prevent metabolie oxidation of the 15-position alcohol function. 

Prostaglandins stimulate the myometrium of the gravid uterus to contract in a manner that is similar to the contractions seen in the term uterus during labor. Carboprost tromethamine, for IM use only, is administered in an initial dose of 250 meg, with subsequent doses of 250 meg at 2 to 4 hour intervals, and not exceeding a total dose of 12.0 mg. Dinoprostone (Prostaglandin E2) is administered by vaginal... 

Carboprost tromethamine (Prostin/15M) Synthetic prostaglandin which stimulates uterine contraction. Regulate smooth muscle tone, coagulation, and body temperature. Abortion during 2nd trimester. ... 

---