Carbonyl compounds Julia coupling

Satoh, T., Hanaki, N., Yamada, N., Asano, T. A Sulfoxide Version of the Julia-Lythgoe Olefination A New Method for the Synthesis of Olefins from Carbonyl Compounds and Sulfoxides with Carbon-Carbon Coupling. Tetrahedron 2000, 56, 6223-6234. 

Modified Julia reactions The Kocienski modification of the Julia reaction Direct Coupling of Carbonyl Compounds and Alkenes... 

In its original form,94 the Julia reaction consisted of the formation of a carbon-carbon double bond through the coupling of a sulfonyl-stabilized anion and a carbonyl compound to generate a P-hydroxy sulfone, followed by a reductive elimination to afford the alkene (Eq. 47). A subsequent study of its scope and stereochemistry led to improved reaction conditions, which are now widely used.206 Alternative methods to synthesize the P-hydroxy sulfone intermediates, such as the addition of sulfonyl carbanions to esters with subsequent reduction of the ketone to the P-hydroxy sulfone, are also known (Eq. 121).207... 

In 1991, Sylvestre Julia reported a direct synthesis of olefins from carbonyl compounds and lithiated heterocyclic sulfones [132-134]. After the initial coupling... 

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