Carbon tetrachloride, interaction model

According to the electrostatic model the solvation is due to electrostatic interaction between the charged ions and the dipolar solvent molecules. Thus the solvating and ionizing properties of a solvent are considered as being due primarily to the dipole moment of the solvent molecules. Thus, ionic compounds such as sodium chloride are insoluble in non-polar solvents such as carbon tetrachloride. Actually, rather than the dipole moment the field action of the dipoles should be considered. This approach might explain why acetonitrile (p = 3.2) is poor in its ionizing properties compared to water (p = 1.84). However, no numerical values are available for this quantity. 

This LSR-CSA technique (discussed in detail in ref. 76) has also been appUed to a series of sulfoxides. Nitroarylsulfoxides are also capable of a strong three-point interaction with fluoroalcohols 1, an ability that is responsible for a considerable difference in stability between the solvates. Mixtures of Id and 2,4-dinitrophenyl methyl sulfoxide are red, and the intensity of this color is inversely proportional to temperature, consistent with formation of tt-tt complexes. Crystallization of the racemic sulfoxide from carbon tetrachloride solutions of (/ )- d leaves mother liquor enriched in the (i )-sulfoxide enantiomer, that predicted by the usual solvation model (41), to form the more stable solvate. With this compound it is also apparent that the (/ , iS )-solvate may differ considerably from the predicted conformation, by population of 42. This additional interaction. 

El-Masri HA, Thomas RS, Sabados GR, Phillips JK, Constan AA, Benjamin SA, Andersen, ME, Mehendale HM, Yang RSH. 1996a. Physiologically based pharmacokinetic/phar-macodynamic modeling of the toxicologic interaction between carbon tetrachloride and kepone. Arch Toxicol 70 704-713. 

J. Fisher, M. Lumpkin, J. Boyd, D. Mahle, J. Bruckner, and H. A. El-Masri, PBPK modeling of the metabolic interactions of carbon tetrachloride and tetrachloroethylene in B6C3F1 mice. Environ Toxicol Pharmacol 16 93-105 (2004). 

The tetrachloride liquids XCiti (X = C, Si, Ti, V, Ge, Sn etc) make an interesting series for studying aspects of orientational correlation in relation to molecular contours. The various diffraction studies have been surveyed in a paper [253 which uses the reference interaction site model (RISM) to evaluate the partial distribution functions. Data for carbon tetrachloride are particularly instructive as they Illustrate the complementary nature of X-ray and neutron scattering. There are three partial functions gcc( )> weighting factors... 

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