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Carbohydrates glycoprotein attachment

Core pentasaccharide Man(a1-6)[Man(a1-3)]Man()J1-4)GlcNAc(/S1-4)GlcNAc of JV-glycoproteins attached to the consensus sequence Asn-Xaa-Ser/Thr. Solid arrows indicate the points of attachment of the outer ami saccharides forming carbohydrate chains, caiied antennae, in addition, the inner-core may be substituted by several monosaccharides dashed arrows)... [Pg.1741]

There is among glycoproteins much heterogeneity due to small differences in the composition of the carbohydrate moieties attached to the... [Pg.4]

Fig. 3.4 The glycosylation pathway via ER and Golgi apparatus, in the cytosol carbohydrates are attached to a lipid precursor, which is then transported into the lumen of the ER to finish core glycosylation. This glycan is now attached to the nascent, folding polypeptide chain (which is synthesized by ribosomes attached to the cytosolic side of the ER from where it translocates into the lumen) and subsequently trimmed and processed before it is folded and moved to the Golgi apparatus. Capping of the oligosaccharide branches with sialic acid and fucose is the final step on the way to a mature glycoprotein [23]. Fig. 3.4 The glycosylation pathway via ER and Golgi apparatus, in the cytosol carbohydrates are attached to a lipid precursor, which is then transported into the lumen of the ER to finish core glycosylation. This glycan is now attached to the nascent, folding polypeptide chain (which is synthesized by ribosomes attached to the cytosolic side of the ER from where it translocates into the lumen) and subsequently trimmed and processed before it is folded and moved to the Golgi apparatus. Capping of the oligosaccharide branches with sialic acid and fucose is the final step on the way to a mature glycoprotein [23].
Glycoprotein A long, spikelike molecule made of carbohydrate and protein that projects beyond the surface of a cell or viral envelope some viral glycoproteins attach the virus to receptor sites on host cells, while other said fusion of viral and cellular membranes. [Pg.1139]

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Carbohydrates glycoproteins

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