Carbamazepine drinking water

McDowell DC, MM Huber, M Wagner, U von Gunten, TA Ternes (2005) Ozonation of carbamazepine in drinking water identification and kinetic study of major oxidation products. Environ Sci Technol 39 8014-8022. 

In the USA, where similar studies have been carried out in treated waters and streams,Stackelberg and co-workers have demonstrated that many of the PPCPs can survive conventional drinking-water-treatment and occur in potable water supplies. Although concentrations in finished water were low (93%<0.5pg L ) and the maximum possible lifetime intake of, for example, carbamazepine would be only 13 mg, compared with a single therapeutic dose of 100 mg, little is known about potential health effects associated with chronic ingestion via drinking water. 

The National Institute for Public Health and Environment (RIVM) in the Netherlands carries out periodical analysis to record the distribution of human and veterinary medicines in drinking water. In 2002 and 2003 [14] during measurements, there were remainders of four active substances found in drinking water and drinking water sources. These four medicines were (acetyl)salicylic acid, carbamazepine, clofibric acid, sulfamethoxazol. In follow-up research in 2005 and 2006 [15, 16] 22 medicines were found and the researchers concluded that this result indicated an... 

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