Cannabinoids Narcotics

Because drug testing for controlled substances bears heavily on a person s reputation, the method to detect controlled substance must be accurate and must follow international guidelines, which advocate a method that must include chromatographic separation to isolate the analyte from other matrix components and mass spectrometric detection with either SIM of three compound-specific ions on a single mass analyzer or with selected-reaction monitoring (SRM) of two specified precursor-product reactions. GC/MS and LC/MS methods that follow these guidelines are used routinely to detect and quantify cannabinoids, narcotics, cocaine, amphetamines, and other substances of abuse [57]. 

Fig. 11. Scanning electron microscope picture of a stalked glandular hair from a bracteole (seed covering) magnified 400 times. Cannabinoids are concentrated in the round head. The rectangular lumpy "bricks" are ceils. (Reprinted from Fairbairn, Bulletin on Narcotics. Vol. 24,1972.)...

Fig. 14. Gas chrocnatograms showing cannabinoid contant of various parts of nnale and female Lebanese marijuana. In this example the small (upper) leaves of the male have the highest THC content and most parts of the female have more CBO than THC—a common finding for Lebanese plants. For a more detailed explanation of chromatography see the testing section of this book. (Reprinted from A. Ohisson et al., Bulletin on Narcotics, Vol. 23,1971.)...

Mechoulam, Chemistry and Biochemistry of Cannabis," 76 75 L.E. Hollister, Tetrahydrocannabinol Isomers and Homologues Contrasted Effects of Smoking, Nature 111 (1970) 968 G.W. Kinzer et al., The Fate of the Cannabinoid Components of Marijuana During Smoking, Bulletin on Narcotics 26 (1974) 41 A.R. Patel and G.B. Gori, Preparation and Monitoring of Marijuana Smoke Condensate Samples, Bulletin on Narcotics 27 (1975) 47. 

L. Grlic, Peroxide-Sulphuric Acid Test As An Indication of the Ripeness and Physiological Activity of Cannabis Resin, Journal of Pharmacy and Pharmacology 13 (1961) 637 A. Dronyssion-Asteriou and C.J. Miras, "Fluorescence of Cannabinoids, Bulletin on Narcotics 26(1974) 19. 

Dronyssion-Asterious, A., and Miras, C.J. Fluorescence of Cannabinoids. Bulletin on Narcotics 26 (1974) 19. 

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