Candida intertrigo

Nystatin is mainly used to treat vaginal and oral infections and localized skin lesions, including Candida intertrigo and Candida nappy dermatitis. It may also be used as prophylaxis during treatment with antibiotics. 

Candida albicans can be isolated in the majority of cases of chronic paronychia. The yeast has traditionally been considered to play an etiological role in the condition, but bacteria and irritant or allergic contact dermatitis also play a role, although the contribution of each varies from patient to patient. A more recent proposal is the primary role of repeated contact with various kinds of foods. Proteins of foods could induce a protein contact dermatitis (Tosti et al. 1992) and, secondarily, an infection by Candida albicans. The primary role of the yeast is, therefore, minimised. Professions at risk, apart from those already quoted as prone to develop Candida intertrigo of the interdigital folds, include all categories... 

Candida intertrigo requires specific therapy. Topical imidazoles are commonly used for a period of 2 weeks, but a longer period of treatment is sometimes needed. When the toe webs are involved, attention should be given to treating concomitant bacteria potassium permanganate soaks (1 part in 10,000) are, therefore, advisable. In general, systemic treatment is not considered for this indication. 

Fig. 13. Candida intertrigo of an interdigital fold with paronychia...

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