Calpan - Calcium pantothenate

The major producers of the calcium salt of pantothenic acid and panthenol are Hoffmann-La Roche, Daiichi, BASF, and Alps. Racemic panthenol is used mainly in hair care products, whereas (R)-panthenol is exclusively used in top-of-the-line, more expensive skin and hair care products. The current (ca 1997) price of (R,3)-panthenol varies between 12 and 18 per kg, that of D-panthenol varies between 30 and 45 per kg, and that of D-calcium pantothenate (Calpan) varies between 22 and 30 per kg. 

Calcium Pantothenate USP, FCC Calcium D-pantothenate Lutavit Calpan Feed Grade Ritapan CAP 137-09-7... 

Currently, (J )-pantothenic acid is industrially produced by conventional chemical synthesis and marketed as the calcium salt (calpan). The global market of calpan was valued at approximately 75 million US dollars in sales in 2005 with a world output over 10 000 ton. The key starting material for large-scale chemical processes is (J )-pantolactone. This molecule can be coupled with either calcium P-alanine to form (J )-pantothenate or with 3-aminopropanol to form panthenol, an important ingredient in skin and hair care consumer products. Purification of (7 )-pantolactone from racemic mixtures occurs by chemical or enzymatic racemic resolution [320, 321]. 

Lutavit B6. See Pyridoxine HCI Lutavit B12. See Cyanocobalamin Lutavit C Cryst. See L-Ascorbic acid Lutavit Calpan Feed Grade. See Calcium D-pantothenate... 

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