Calcium protein and

Coroneo MT, Maier H, Schindler JG, Heidland A. The secretion of ionised and total calcium, protein and inorganic phosphate by the salivary glands of rat and man. In Saliva and Salivation. Advances in Physiological Sciences, vol. 28. Zelles T, ed. 1980. Pergamon Press, Akademiai Kiado, Budapest, pp. 289—294. 

Due to the report by Manalis and Cooper in 1973 that lead inhibits calcium-triggered release of neurotransmitters (452), much attention has focused on the possibility that lead interacts with calcium proteins and/or affects calcium homeostasis (40, 173, 338-340, 351, 355, 443, 453 64). Indeed, patch clamp studies reveal that lead blocks voltage-dependent calcium channels (459, 464, 465), but the effects are highly dependent on the channel and cell type (460). In addition, lead has been shown to stimulate efflux from nerve cells via Ca -ATPase in a calmodulin-dependent fashion, resulting in a net decrease in... 

DFT calculations. This system provides an effective model for Ca sites in biological materials due to the similarity of its calcium coordination to that in many calcium proteins and relevance to natural phenomena such as biomineralisation. 

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