Purkinje cells calbindin

Whitney ER, Kemper TL, Bauman ML, Rosene DL, Blatt GJ (2008) Cerebellar Purkinje cells are reduced in a subpopulation of autistic brains a stereological experiment using calbindin-D28k. 

Fig. 31. A. Calbindin-D28k immunoreactivity. B. Parvalbumin-immunoreactivity in rat cerebellar cortex. Purkinje cells react with both antibodies arrows in B indicate parvalbumin- immunoreactive stellate and basket cells. Bar = 50 gm. Courtesy of Dr. M.P.A. Schalekamp.

Several polypeptides, that are present in all Purkinje cells, but not in other cells of the cerebellum, have been mentioned in the previous sections of this chapter. They include the IP3 receptor (identical to the P400 protein and to the PCPP-260 protein of Walaas et al., 1986) (see Section 3.1.4), IPj-S-kinase (Section 3.1.4), cGMP-dependent protein kinase (Section 3.1.5), PEP-19 and calbindin-D28K (Section 3.1.7). Two other... 

Fig. 1 Combined immunoperoxidase labeling and neurotracing. Cerebellar Purkinje cells of wild-type mouse at P10 have been labeled with an anti-calbindin antibody and the immunoperoxidase reaction was developed with non-intensified DAB brown) after neurotracing of climbing fibers following injection of the anterograde tracer BDA into the inferior olive and development with cobalt-intensified DAB (blacK). BDA biotinylated dextran amine, ca/6 calbindin, CF climbing fiber, PC Purkinje cell. Bars=A, 20 (im B, 10 (im...

Nakagawa S, Watanabe M, Isobe T et al (1998) Cytological compartmentalization in the staggerer cerebellum, as revealed by calbindin immunohistochemistry for Purkinje cells. J Comp Neurol 395 112-120... 

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