Caffeine clusters

FIGURE 31.7 A 50 50 mixture of natural and synthetic caffeine does not fall into either the 100% natural caffeine cluster nor the 100% synthetic caffeine cluster. 

FIGURE 7.2 Caffeine rejection rate (o) and permeability constant ( ) obtained during caffeine/SC CO2 separation on a nanofilter having a thin layer of Zr02-Ti02 ( = 308 K, transmembrane pressure = 0.2 MPa). Values of estimated cluster size for each experimental point are indicated. (Adapted from Chiu, Y.-W. and Tan, C.-S., J. Supercrit. Fluids, 21, 81, 2001.)... 

FIGURE 31.6 (See color insert following page 622.) Clusters of natural caffeine and S5mthetic caffeine. 

Figure 31.6 shows a cluster analysis of synthetic and natural caffeine. Although the chemical entity is the same, the processing conditions are sufficiently different to allow separation between the two materials, based on teaching the system multiple samples of both products. Figure 31.7 shows that a 50 50 mix of synthetic and natural caffeine does indeed fall outside the range of both the natural and synthetic clusters. 

---