Cacospongia linteiformis

This compound also showed antispasmodic activity [122], A variety of cytotoxic compounds was isolated, including a bishomosesterterpene and dysidiolide from another Dysideci sp., a sulfated sesterterpene hydroquinone from a Hippospongia sp., and two new sesterterpenes, lintenolides F and G from the Caribbean sponge Cacospongia linteiformis [123,124],... 

From the Caribbean sponge Cacospongia linteiformis was isolated lintenone (156) with a new tricarbocyclic skeleton, which contains fused cyclohexane, cyclopentane and cyclobutane rings. Lintenone exhibited high antifeedant activity against the fish C. aurantus (30 pg per cm2 of food pellets), ichthyotoxicity to G. affinis (10 ppm) and moderate toxicity in A. salina assay (LC50 109 ppm) [166]. 

Fattomsso, E., Lanzotti, V, Magno, S., and Mayol, L. (1992) A novel bioactive sesterterpene based on an unprecedented tricydic skeleton from the Caribbean sponge Cacospongia cl. linteiformis. J. Org. Chem., 57, 6921-6924. 

---