4- /«7-Butyl-2,5-dimethylphenol

PEROXIDES AND PEROXIDE COMPOUNDS - ORGANIC PEROXIDES] (Vol 18) 2-tert-Butyl-4,6-dimethylphenol [1879-09-0]... 

Examples of palladium-catalyzed reduction are 4-chloro-2,6-di-r-butyl-phenol to 2,6-di-t-butylcyclohexanone (750 psig, 25 C) with loss of halogen 24), 1,8-dihydroxynaphthalene to 8-hydroxy-1-tetralone 30), and 2,4-dimethylphenol to 2,4-dimethylcyclohexanone (27). 

McCracken, P. G. Bolton, J. L. Thatcher, G. R. J. Covalent modification of proteins and peptides by the quinone methide from 2-ZerZ-butyl-4,6-dimethylphenol selectivity and reactivity with respect to competitive hydration, j. Org. Chem. 1997, 62, 1820-1825. 

K. Mizutani, T. Electronic and structural requirements for metabolic activation of butylated hydroxytoluene analogs to their quinone methides, intermediates responsible for lung toxicity in mice. Biol. Pharm. Bull. 1997, 20, 571-573. (c) McCracken, P. G. Bolton, J. L. Thatcher, G. R. J. Covalent modification of proteins and peptides by the quinone methide from 2-rm-butyl-4,6-dimethylphenol selectivity and reactivity with respect to competitive hydration. J. Org. Chem. 1997, 62, 1820-1825. (d) Reed, M. Thompson, D. C. Immunochemical visualization and identification of rat liver proteins adducted by 2,6-di- m-butyl-4-methylphenol (BHT). Chem. Res. Toxicol. 1997, 10, 1109-1117. (e) Lewis, M. A. Yoerg, D. G. Bolton, J. L. Thompson, J. Alkylation of 2 -deoxynucleosides and DNA by quinone methides derived from 2,6-di- m-butyl-4-methylphenol. Chem. Res. Toxicol. 1996, 9, 1368-1374. 

Acetamido-4-amino-6-chloro-s-triazine, see Atrazine Acetanilide, see Aniline, Chlorobenzene, Vinclozolin Acetic acid, see Acenaphthene, Acetaldehyde, Acetic anhydride. Acetone, Acetonitrile, Acrolein, Acrylonitrile, Aldicarb. Amyl acetate, sec-Amyl acetate, Bis(2-ethylhexyl) phthalate. Butyl acetate, sec-Butyl acetate, ferf-Butyl acetate, 2-Chlorophenol, Diazinon. 2,4-Dimethylphenol, 2,4-Dinitrophenol, 2,4-Dinitrotoluene, 1,4-Dioxane, 1,2-Diphenylhydrazine, Esfenvalerate. Ethyl acetate, Flucvthrinate. Formic acid, sec-Hexyl acetate. Isopropyl acetate, Isoamyl acetate. Isobutyl acetate, Methanol. Methyl acetate. 2-Methvl-2-butene. Methyl ferf-butvl ether. Methyl cellosolve acetate. 2-Methvlphenol. Methomvl. 4-Nitrophenol, Pentachlorophenol, Phenol. Propyl acetate. 1,1,1-Trichloroethane, Vinyl acetate. Vinyl chloride Acetoacetic acid, see Mevinphos Acetone, see Acrolein. Acrylonitrile. Atrazine. Butane. 

OxymetazoUne Oxymetazoline, 6-fert-butyl-3 (2-imidazolin-2-ilmethyl)-2,4-dimethylphe-nol (11.1.39), is synthesized by chloromethylation of 6-tert-butyT2,4-dimethylphenol and the further transformation of the resulting chloromethyl derivative (11.1.37) into a nitrile (11.1.38). The reaction of this with ethylendiamine gives oxymetazoline (11.1.39) [41,42]. 

Simple alkyl esters show rather low stereoselectivity. However, highly hindered esters derived from 2,6-dimethylphenol or 2,6-di-/-butyl-4-methylphenol provide the anti stereoisomers. 

The oxidative polymerization reaction is rapid at room temperature. Oxidation of 2.6-dimethylphenol readily gives high polymer with only a minor amount of the diphenoquinone (VIII R=R1=CH3). This polymer is now being produced commercially. In general when the substituents are small (Table 4) the polymer is formed preferentially (35). If one of the substituents is as large as tert-butyl or both as large as isopropyl then the diphenoquinone is preferentially formed. 

Phenols/cresols Phenol, 2,5-dimethylphenol, 3,5-dimethylphenol, 2,6-di-tert-butyl-4-methylphenol, o,m,p-cresol, p-tetramethylbutylphenol, nonylphenols, 2,6-di-tert-butyl-4-methoxymethylphenol, 2,6-di-tert-butyl-4-methylphenol, 4,4 -butyliden-bis-(6-tert-butyl) -m-cresol, C-8-alkylphenols, C-9-alkylphenols... 

Pd-catalyzed CO- bond forming reactions were performed by Buchwald [8] et al. with 2-dimethylamino-2 -di-(tert.-butyl)-biphenyl as ligand. 3,4-Dimethylphenol can be arylated smoothly with 2-chloro-4-methyl-toluene in the presence of sodium hydride [eq. (f)]. 

Copolymerization of 4-bromo-2,6-dimethylphenol with 2,4,6-trimethylphenol, 4-t-butyl-2,6-dimethylphenol, 2,2-bis(4-hydroxy-3,5-dimethylphenyl)propane, 4-hydroxy-3,5-dimethylbenzyl alcohol and a 4-substituted-2,6-di-r-butylphenol are discussed269. 

Polycondensates were prepared from pyrocatechol, o-cresol, p-cresol, mixtures of the latter with 2,4-dimethylphenol,2-tert-butyl-4-methylphenol, di-scc-butyl-phenol or other monoalkylphenols and their mixtures with dialkylphenols or alkoxyphenols. 

Cl2H17Br02 1-bromO 3-adamantyl hydroxymethyl ketone 73599-91-4 526.15 46.402 1,2 24433 C12H180 2-tert-butyl-4,5-dimethylphenol 1445-23-4 531.65 46.933 1,2... 

C11H25N diethylheptyl amine 26981-81-7 215.00 27.267 2 24434 C12H180 2-tert-butyl-4,6-dimethylphenol 1879-09-0 295.45 24.372 2... 

C11H25N 4-ethyl-1 -methyl octyfamine 10024-78-9 288.26 35.332 2 24436 C12H180 4-tert-butyl-2,5-dimethylphenol 17696-37-6 344.35 24.372 2... 

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