Burkholderia cenocepacia

The high sensitivity and reproducibility of currently used instruments also allows to directly monitor the binding of small ligands, i.e. disaccharides or monosaccharides, to immobilized lectins.75 77 Fig. 3 illustrates the binding of small glycans to BclA lectin from Burkholderia cenocepacia.26... 

Fang K, Zhao H, Sun C et al (2011) Exploring the metabolic network of the epidemic pathogen Burkholderia cenocepacia J2315 via genome-scale reconstruction. BMC Syst Biol 5 83... 

Ortega, X., Silipo, A., Saldfas, M.S., Bates, C.C., Molinaro, A., Valvano, M.A. Biosynthesis and structure of the Burkholderia cenocepacia K56-2 lipopolysaccharide core oligosaccharide truncation of the core oligosaccharide leads to increased binding and sensitivity to polymyxin B. J Biol Chem 284(32) (2009) 21738-21751. 

Burkholderia cenocepacia is another opportunistic bacterium that, alike P. aeruginosa, infects patients suffering from CF. Four lectins have been identified in B. cenocepacia and each contains at least one domain with strong sequence similarity to LecB described above. For example, the BC2L-C lectin is a most interesting construction, as this elongated molecule displays different lectin activities at its two ends (Fig. a novel... 

Mohamed, Y. F. and Valvano, M. A. (2014) A Burkholderia cenocepacia Mur J (MviN) homolog is essential for cell wall peptidoglycan synthesis and bacterial viability. Glycobiology 24, 564-576. 

Wang, H., Sim, H., and Wei, D. (2013). Discovery and characterization of a highly efficient enantioselective mandelonitrile hydrolase from Burkholderia cenocepacia J2315 by phylog-eny-based enzymatic substrate sp>ecificity prediction. BMC Biotechnology, 13,14. 

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