2-Bromo-4,5,6-trichlorophenol

Bromo-3,4,6-trichlorophenol. 2,4,5-Trichlorophenol (20 grams, 0.10 mole) was dissolved in 40 ml of glacial acetic acid (HOAc). Bromine (17 grams, 0.11 mole) dissolved in HOAc was added to the phenol, and the mixture was heated to 100°C. The color of bromine persisted until 30 ml of water were added. The reaction mixture yielded yellow-tinted crystals upon cooling. The product formed an oil when dissolved in methanol or HOAc—H2O. The phenol was converted to its potassium salt by adding KOH and evaporating the solvent. 

Bromo-4,5,6-trichlorophenol. 2,3,4-Trichlorophenol (20 grams, 0.10 mole) was dissolved in 30 ml of HO Ac and titrated with bromine (18 grams, 0.11 mole) dissolved in HOAC-H2O (30 ml each). The last few drops of bromine caused the characteristic color of bromine to persist. The product was precipitated by adding water to the reaction mixture. The filtered product was recrystallized from methanol-water solvent yielding 27 grams (98% yield) of white crystals. 

Bromo-2-nitropropane-1,3-diol Calcium disodium EDTA p-Chloro-m-cresol Dichlorophene Diiodomethyl tolylsulfone Dimethyl oxazolidine Laurtrimonium chloride Pine (Pinus palustris) oil Poly (hexamethylenebiguanide) hydrochloride Sodium 2-mercaptobenzothiazole 2-Thiocyanomethylthiobenzothiazole Tributyltin oxide 2,4,6-Trichlorophenol preservative, timber Zinc arsenite preservative, tissues... 

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