Breakthrough, resin, organic compounds

To estimate the size column required to isolate more of this polar material, we used information published by Thurman et al. (16), who described an empirical relationship between aqueous solubility of organic compounds and capacity factors on XAD-8 resin. They defined capacity factor as the mass of solute sorbed on the resin divided by the mass of solute present in the void volume of the column at the 503> breakthrough point. On the basis of their data, a substance having a capacity factor of 1000 will have a solubility of about 1 X 10-3 mol/L. Examples of compounds having solubility in this range are methyl benzoate, 2,4,6-trichlorophenol, and chlorobenzene. 

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