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Brain tumors therapeutic targets

Brain microvascular EC monolayers together with an astrocyte-enriched subendothelial collagen gel can be used to simulate the blood-brain barrier (BBB) (39). Such systems are invaluable to screen for compounds able to penetrate the BBB to access brain tumors or metastases. In addition, glioma cell invasion into brain fragments has enabled better understanding of the properties of these highly invasive tumors and identification of potential therapeutic targets (40). [Pg.234]

Brigger, J. Morizet, G. Aubert, H. Chacun, M.J. Terrier-Lacombe, P Couvreur, and G. Vassal, Poly(ethylene glycolj-coated hexadecylcyanoacrylate nanospheres display a combined effect for brain tumor targeting. The Journal of Pharmacolocy and Experimental Therapeutics, 303 (3), 928-936,2002. [Pg.278]

Delac, M., Motaln, H., Ulrich, H., Lah, T.T., 2015. Aptamer for imaging and therapeutic targeting of brain tumor glioblasto. Cytometry A 87A, 806-816. [Pg.236]

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See also in sourсe #XX -- [ Pg.263 ]



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Brain targeting

Targeted therapeutics

Targets targeted therapeutics

Therapeutic targeting

Therapeutic targets

Tumor brain tumors

Tumor therapeutics

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