Bolaamphiphilic peptide nanotubes

Copper has been immobilized on glycylglycine bolaamphiphile peptide nanotubes that display histidine residues, and paramagnetic gadolinium, a magnetic resonance image contrast agent, has been immobilized on nanofibers produced from peptide amphiphiles (see Gazit, 2007 and references therein). 

Molecules like bi5(A-a-amido-Gly-Gly)-l,7-heptane di-carboxylic acid (Fig. 6) belong to a class of compounds called bolaamphiphiles that form tubular aggregates at low These peptide nanotubes have diameters in... 

The self-assembly of bolaamphiphiles into potentially useful nano- and microstructures has been the subject of intense studies in recent years. These molecules contain both peptide and nonpeptide segments (Figure 14a-f) and, over the course of several days in water, they form nanotubes with a wide range of diameters, ranging from 20 nm to 1 om. In order to control the diameter, nanotubes have been prepared within polycarbonate membranes. 

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