Boehringer Mannheim Corporation

Elements with similar functions but different construction and configuration are also available. For illustrative purposes, the cross settions of two elements, developed by Boehringer Mannheim Corporation (BMC) (39) and Fuji Photo... 

Martin Gerber, Boehringer Mannheim Corporation, Indianapolis, USA Karl Wulff, Boehringer Mannheim GmbH, Mannheim, FRG... 

Boehringer Mannheim Corporation, Biochemical Products, 9115 Hague Road, P.O. Box 504 Indianapolis, IN 46250-0414, USA. 

Boehringer Mannheim Corporation, 47 City University of New York, 124,169 Colorado State University, 158 Delft University of Technology, 34 Eli Lilly and Company, 84 Firestone Building Products Company, 2 Georgetown University, 252 Kumamoto University School of Medicine, 194 Kyushu University, 238 National Institute of Bioscience and Human Technology, 41 National Tsing Hua University, 276 Naval Research Laboratory, 252,264 Polytechnic University, 124,169... 

Fig. 8. Morphological changes of apoptotic eosinophils induced by dexamethasone (Z2). After eosinophils were treated (a) without or (b) with dexamethasone (2 /u,M) for 12 h, cells were harvested and detected by TUNEL assay using the In Situ Cell Death Detection Kit (Boehringer Mannheim). Briefly, cells were fixed with 4% paraformaldehyde and permeabilized by proteinase K and incubated with the TUNEL reaction mixture containing terminal deoxynucleotidyl transferase (TdT). After washing to remove unbound enzyme conjugated antibody, the horseradish peroxidase retained in the immune complex was visualized by a substrate reaction with diaminobenzidine. The cell nucleus was counterstained with methanol green. Apoptotic eosinophils with nuclear DNA breaks were seen to stain dark brown using a Nikon Eclipse E800 microscope (Nikon Corporation, Tokyo, Japan) in Fig. 8b.

As of April 2009, the membership has consisted of ten multinational pharmaceutical corporations (AZ, Boehringer Mannheim, GSK, Johnson Johnson, Lilly, Merck, Novartis, Pfizer, Schering-Plough, and Wyeth), and two technology/suppler organizations (Codexis and DSM). 

We wish to thank the symposium contributors for their efforts to help write this book. We would ako like to thank the following companies for contributing to the symposium Unitika Ltd., Monsanto Agricultural Company, Glaxo, Genzyme, Boehringer Mannheim Biochemicals, Rohm and Haas, Procter and Gamble, Polaroid Corporation, and the Division of Carbohydrate Chemistry of the American Chemical Society. A special... 

Materials All chemicals were of reagent grade. Restriction enzymes and enzjnnes for cloning and sequencing were from Pharmacia, Boehringer Mannheim and U.S. Biochemical Corporation. Radioactive nucleotides were from Amersham. 

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