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Blood-surface interaction, influencing factors

A study has been carried out on the interactions of blood with plasticised poly(vinyl chloride) biomaterials in a tubular form. The influence of different factors such as the biomaterial, antithrombotic agent, blood condition and the nature of the application is represented when considering the blood response in the clinical utilisation of the plasticised PVC. The PVC was plasticised with di-(2-ethylhexyl)phthalate (DEHP) and tri-(2-ethylhexyl)trimellitate (TEHTM)and in-vitro and ex-vivo procedures used to study the biomaterial with respect to the selection of the plasticiser. The blood response was measured in terms of the measurement of fibrinogen adsorption capacity, thrombin-antithrombin III complex and the complement component C3a. X-ray photoelectron spectroscopy was used for surface characterisation of the polymers and the data obtained indicated that in comparison with DEHP-PVC, there is a higher reactivity... [Pg.113]

See other pages where Blood-surface interaction, influencing factors is mentioned: [Pg.39]    [Pg.131]    [Pg.244]    [Pg.256]    [Pg.363]    [Pg.217]    [Pg.21]    [Pg.355]    [Pg.287]    [Pg.261]    [Pg.165]    [Pg.131]    [Pg.144]    [Pg.402]    [Pg.3666]    [Pg.99]    [Pg.352]    [Pg.461]    [Pg.275]    [Pg.218]    [Pg.352]   
See also in sourсe #XX -- [ Pg.509 ]



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Interactions, influencing factors

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