Blood, glucose-6-phosphatase

Skeletal muscle cannot contribute directly to blood glucose because it does not contain glucose-6-phosphatase. 

In a person with glucose 6-phosphatase deficiency, ingestion of galactose or fructose causes no increase in blood glucose, nor does administration of glucagon or epinephrine. 

Since the enzyme glycogen synthase catalyses the rate-limiting step in glycogen synthesis, it is the activity of this enzyme that must be increased as the blood glucose concentration increases. This is achieved via an interconversion cycle (i.e. reversible phosphorylation). A protein kinase phosphorylates it, which inactivates the enzyme, whereas a protein phosphatase dephosphorylates it, which... 

Hepatio Renal Endoor 100 mg/kg/d 100 mg/kg/d 100 mg/kg/d (Increased Mg ATPase, acid phosphatase, and glucose-6-phosphatase activities) (Increased Mg ATPase activity) (Increased blood glucose) sulfate... 

Isoproterenol is the most potent stimulant of skeletal muscle glycogenolysis, followed by epinephrine and norepinephrine. (3z-Adrenoceptors mediate muscle glycogenolysis. Stimulation of skeletal muscle glycogenolysis will raise blood lactic acid levels rather than blood glucose levels because skeletal muscle lacks the enzyme glucose-6-phosphatase, which catalyzes the conversion of glucose-6-phosphate to glucose. 

Blood glucose, liver enzymes, and serum alkaline phosphatase, bilirubin, and potassium, AST (SCOT), and ALT (SGPT) levels... 

This phosphatase converts phosphorylase a to phosphorylase b, sharply reducing the activity of phosphorylase and slowing glycogen breakdown in response to high blood glucose. Insulin also acts indirectly to stimulate PP1 and slow glycogen breakdown. 

The insulin-enhancing activity of vanadium compounds is likely to be related to their interactions with cellular redox chemistry and ROS formation, in addition to direct inhibition of PTP-1B and other protein phosphatases as a transition-state analogue [100], Differences in the effects of V (III, IV or V)-dipicolinic acid complexes on blood glucose and absorption of V into serum after chronic oral admin-... 

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