Bladder hyperreflexia

Disease states in which currently available capsaicin solutions or creams are clearly beneficial, such as non-allergic (vasomotor) rhinitis (Stjarne et al., 1989 Lacroix et al., 1991 Marabini et al., 1991 Filiaci et al., 1994), urinary bladder hyperreflexia (Fowler et al., 1992 Geirsson et al., 1995) and notalgia parestetica (Leibsohn, 1992). 

Cruz, F., Guimaraes, M., Silva, C., Reis M. Suppression of bladder hyperreflexia by intravesical resiniferatoxin, Lancet 1997, 350, 640-641. 

Both capsaicin and RTX have also been tested as treatments for a condition called bladder hyperreflexia, which is characterized by the nrge to nrinate even when there is very little nrine in the bladder. Capsaicin effectively relieved the problem when it was instilled into the nrinary bladder, but the first application cansed an intense bnming sensation that was... 

Cruz, F. Desensitization of bladder sensory fibers by intravesical capsaicin of capsaicin analogs, a new strategy for treatment of urge incontinence in patients with spinal detrusor hyperreflexia or bladder hypersensitivity disorders. Inter. Urogynecol. Journal 1998, 9, 214-220. 

Bauer (1992) grouped into primarily unstable bladder (small capacity, hypertonic bladders and detrusor hyperreflexia), infrequent voiding associated with large-capacity bladders (lazy bladder syndrome) and psychogenic nonneuropathic bladder (Hinman syndrome). 

---