Detrusor hyperreflexia

Cruz, F. Desensitization of bladder sensory fibers by intravesical capsaicin of capsaicin analogs, a new strategy for treatment of urge incontinence in patients with spinal detrusor hyperreflexia or bladder hypersensitivity disorders. Inter. Urogynecol. Journal 1998, 9, 214-220. 

Geirsson, G., Fall, M., Sullivan, L. Clinical and urodynamic effects of intravesical capsaicin treatment in patients with chronic traumatic spinal detrusor hyperreflexia, J. Urol. 1995, 154, 1825-1829. 

Lazzeri, M., Spinelli, M., Beneforti, P., Zanollo, A., Turini, D. Intravesical resiniferatoxin for the treatment of detrusor hyperreflexia refractory to capsaicin in patients with chronic spinal cord diseases, Scandinavian J. Urol. Nephrol. 1998, 32, 331-334. 

MODIFICATIONS OF THE METHOD Either chemical (6-hydroxydopamine, reserpine) or surgical (section of hypogastric nerves) sympathectomy produces a picture of detrusor hyperreflexia and urine dropping, mimicking cystometric finding in human disease (Maggi et al. 1987a). 

Blaivas JG, Labib AB, Michalik SJ, Zayed AAH. Cystometric response to propantheline in detrusor hyperreflexia Therapeutic implications. JUrol 1980 124 259-262. 

Bauer (1992) grouped into primarily unstable bladder (small capacity, hypertonic bladders and detrusor hyperreflexia), infrequent voiding associated with large-capacity bladders (lazy bladder syndrome) and psychogenic nonneuropathic bladder (Hinman syndrome). 

For prognostic and therapeutic reasons, only functional classifications based on the reflex activity of the different muscle groups involved in storing and evacuating urine should be used. One commonly used classification is based primarily on the reflex activity of the detrusor muscle, defining three types contractile detrusor (detrusor hyperreflexia), acontractile detrusor (detrusor areflexia), and intermediate detrusor (mixed type). 

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