Bitter Pill

Schifano, F., A bitter pill. Overview of ecstasy (MDMA, MDA) related fatalities, Psychopharmacology (Berlin) 173(3 4), 242-248, 2004. 

See, for example, S. Fried, Bitter Pills Inside the Hazardous... 

Sarah Adams. Swallowing a bitter pill. Pharmaceutical Formulation Quality. Dec/Jan 2003. 

Melrose, D. 1982. Bitter Pills Medicines and the Third World Poor. Oxford Oxfam. 

Fidel Castro s takeover of Cuba in 1959 had been a bitter pill for the Lansky syndicate to swallow however, it taught the old wizard a valuable lesson don t take politics for granted. Before he socked tens of millions of dollars into his Grand Bahamas dreamland, Lansky would make absolutely certain that he was treading on solid political ground. 

McLean, Bethany, A Bitter Pill, Fortune, August 13, 2001. 

Play around with this tool (but seriously) to teach yourself with whom and what you are really competing, and to make yourself swallow the bitter pill of how your current solution really stacks up. 

Hall, Personalized Medicine s Bitter Pill Arlington et al., Pharma 2010 The Threshold of Innovation. 

Hall, S. "Personalized Medicine s Bitter Pill. Technology Review (February 2003) 63-70. 

Asbury, C.H. Medical Drugs of Limited Commercial Interest Profit Alone is a Bitter Pill. Intern. J. Health Serv. 1981, 11 (3), 451-462. 

The Bohr theory of the atom destroyed the last pockets of resistance to the quantum concept. Yet the wave attributes of light were there too. The nature of light took on a dual aspect. This duality in the nature of light is accepted now, though to some in the beginning it was a bitter pill. 

Senn SJ (2006) Sharp tongues and bitter pills. Significance 3 123-125. 

Families USA Bitter Pill The Rising Price of Prescription Drugs for Older Americans, June 2002, http //www. familiesusa.org/, accessed July 2002. 

A.D. 1900 "That bitter potion is snake oil. Here, swallow this bitter pill "... 

A.D. 1950 "That bitter pill is ineffective. Here, take this bitter antibiotic "... 

The expressions take your medicine and it s a bitter pill are metaphors that refer to doing what s necessary to solve a difficult personal problem. To take your medicine might be unpleasant if it is bitter—and medicines do frequently taste bitter. Why ... 

David Willman, Bitter Pill, Washington Monthly, September 1, 1999, at 33 David Willman, The Rise and Fall of the Killer Drug Rezulin, LAT, June 4,2000, at Ai Marc Kaufman, Controversial Diabetes Drug is Withdrawn, WP, March 22, 2000, at Ar David Willman, Fast-Track Drug to Treat Diabetes Tied to 33 Deaths, LAT, December 6, 1998, at Ai (quote). 

---