2,2 -Bis diphenylphosphino -1,1 -binaphthyl

BINAP 2,2 -bis(diphenylphosphino)-1,1 -binaphthyl KHMDS potassium bis(trimefhylsilyl)amide... 

BINAP [2,2 -bis(diphenylphosphino)-1,1 -binaphthyl] is commercially available or can be prepared according to a literature procedure.3 The diphosphine is slowly oxidized in air to give the corresponding mono and diphosphine oxides that can be removed by column chromatography (silica gel, benzene) under an inert atmosphere. 

Burkholderia cepacia lipase (Amano PS) 2,2 -Bis(diphenylphosphino)-1,1 -binaphthyl Candida antarctica lipase B Diversity-oriented synthesis... 

There are several synthetic pathways that permit the synthesis of undecanuclear clusters. The reduction of the mononuclear precursor [AuI(PPh3)] or the dinuclear precursor [Au2X2(BINAP)] with NaBH4 leads to clusters [ ( 3)713] [28] and [Aun(BINAP)4X2] [29] (X = C1 or Br BINAP = 2,2 -bis(diphenylphosphino)-1,1 -binaphthyl), respectively reaction of gold vapor with complex [Au(SCN)(PPh3)] in ethanol leads to cluster [Auu(PPh3)7(SCN)3]3+ [30] the photolytic reduction of... 

Chiral aluminium complexes have been used as catalysts for inverse electron-demand 1,3-dipolar cycloadditions of alkenes with nitrones, and the first contribution to this field was published in 1999 (344). The chiral AlMe-BINOL (BINOL = 2,2 -bis(diphenylphosphino)-1,1 -binaphthyl) complexes 235 were excellent catalysts for the reaction between nitrone 225a and vinyl ethers 232 (Scheme 12.68). The diastereo- and enantioselectivities are highly dependent on the chiral ligand. An exo/endo ratio of 73 27 was observed, and the exo-product was... 

In 1996, Yamamoto and Yanagisawa reported the allylation reaction of aldehydes with allytributyltin in the presence of a chiral silver catalyst.2 They found that the combination of silver and a phosphine ligand accelerates the allylation reaction between aldehydes and allyltributyltin. After this discovery, they screened several chiral phosphine ligands and found that chiral silver-diphosphine catalysts can effect the reaction in an enantioselective fashion (Table 9.1).2 For example, when benz-aldehyde and allyltributyltin were mixed in the presence of 5 mol% of AgOTf and (S)-2,2 -bis(diphenylphosphino)-1,1 -binaphthyl (BINAP), the corresponding homoallyl alcohol was obtained with 96% ee and 88% yield (Table 9.1). Generally, the reaction with aromatic aldehydes afforded the corresponding homoallyl alcohols in excellent... 

---